Vinblastine sulfate salt

Quality Level

200

Assay

≥97% (HPLC)

form

(powder or amorphous or crystalline powder)

color

white to light yellow

mp

267 °C (dec.) (lit.)

absorption

14 at 270 nm in 0.1 M phosphate buffer at 1 mM
16.2 at 259 nm in ethanol at 1 mM
53.7 at 214 nm in ethanol at 1 mM

antibiotic activity spectrum

neoplastics

Mode of action

DNA synthesis | interferes

originator

Eli Lilly

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.[H][C@@]12CN(CCc3c([nH]c4ccccc34)[C@@](C1)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@]7([H])[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@]89[H])C(=O)OC)C[C@](O)(CC)C2

InChI

1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6 36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2 37(44)50)39(59-27(3)51)46(38 55)41(53)58-7;1-5(2 3)4/h10-14 16 21-22 28 37-39 47 54-55H 8-9 15 17-20 23-26H2 1-7H3;(H2 1 2 3 4)/t28- 37- 38+ 39+ 42- 43+ 44+ 45- 46-;/m0./s1

InChI key

KDQAABAKXDWYSZ-PNYVAJAMSA-N

Gene Information

human … TBCC(6903) TUBA1A(7846) TUBA1B(10376) TUBA1C(84790) TUBA3C(7278) TUBA3E(112714) TUBA4A(7277) TUBB(203068) TUBB1(81027) TUBB2A(7280) TUBB2B(347733) TUBB3(10381) TUBB4A(10382) TUBB4B(10383) TUBB6(84617) TUBB8(347688)